Publications

“There is a clear research gap when it comes to assessing innovative care models that support the scale-up of access to chronic disease prevention and care.  Our aim is to close this gap.”

-Prof. Niklaus Labhardt

Scientific publications

Cohort profile: the open, prospective Community-Based chronic Care Lesotho (ComBaCaL) cohort - design, baseline chronic disease risk factors and hypertension and diabetes care cascades (2025)

Community Health Worker-led versus facility-based hypertension care for people with uncontrolled blood pressure in rural Lesotho: a cluster-randomized trial within the ComBaCaL cohort study (preprint 2025)

Prevalence and factors associated with dementia in Lesotho:A cross-sectional, population-based study (2024)

Prevalence of hepatitis B virus infection and treatment eligibility in Lesotho, Southern Africa: a population-based cross-sectional study with case-based follow-up (2024)

Awareness, treatment, and control among adults living with arterial hypertension or diabetes mellitus in two rural districts in Lesotho (2024)

eConsent administered by Community Health Workers in a study using the Trials within Cohorts (TwiCs) design—Experiences from the Community-Based chronic Care Lesotho (ComBaCaL) project (2024)

Empowering Community Health Workers with Scripted Medicine: A Design Science Research Study (2024)

Community-based management of arterial hypertension and cardiovascular risk factors by lay village health workers for people with controlled and uncontrolled blood pressure in rural Lesotho: joint protocol for two cluster-randomized trials within the ComBaCaL cohort study (ComBaCaL aHT Twic 1 and ComBaCaL aHT TwiC 2) (2024)

Community-based models of care for adolescent and adult depression, suicidal behavior, anxiety, trauma, and substance use in Africa: a scoping review (2024)

Implementing focused echocardiography and AI-supported analysis in a population-based survey in Lesotho: implications for community-based cardiovascular disease care models (2024)

Prevalence of Mental Health and Substance use Problems and Awareness of Need for Services in Lesotho: Results from a Population-Based Survey (2024)

Algorithmic Management for Community Health Worker in Sub-Saharan Africa: Curse or Blessing? (2023)

Community-based type 2 diabetes care by lay village health workers in rural Lesotho: protocol for a cluster-randomized trial within the ComBaCaL cohort study (ComBaCaL T2D TwiC) (2023)

Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey (2023)

High Rates of Undiagnosed Target Organ Damage Among Adults with Elevated Blood Pressure or Diabetes Mellitus in a Community-Based Survey in Lesotho (2023)

Head-to-head comparison of the WHO STEPwise approach with immediate unattended and delayed unattended automated blood pressure measurements during household-based screening: a diagnostic accuracy study in Lesotho (2023)

Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services (2023)

Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: A scoping review (2023)

Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review protocol (2023)

Clinical guidelines

Standard Treatment Guidelines for Lesotho (2022, with contributions from the SolidarMed/ComBaCaL team)